Sequential organ failure assessment (SOFA) score as a predictor of acute kidney injury in COVID-19 patients: a systematic review and meta-analysis

Authors

  • Nicolas Daniel Widjanarko Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia
  • Erich Tamio Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia
  • Steven Alvianto Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia
  • Nadhea Debrinita Surya Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia
  • Rexel Kuatama Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia
  • Maria Riastuti Iryaningrum Department of Internal Medicine, Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

DOI:

https://doi.org/10.36216/jpd.v7i1.206

Keywords:

AKI, COVID-19, SOFA score, predictor

Abstract

Background: The sequential organ failure assessment (SOFA) score is a tool used to describe organ failure in critically ill patients. Studies have showed that coronavirus disease 2019 (COVID-19) patients who develop predictor of acute kidney injury (AKI) often have an increased SOFA. 

Objective: This study aimed to evaluate the potential of SOFA score as a predictor AKI in COVID-19 patients. 

Methods: A systematic search was conducted on PubMed, Google Scholar, EBSCO-Host, and ProQuest. The risk of bias was assessed using the Newcastle-Ottawa Scale . 

Result: Out of the 9 studies reviewed, 7 showed a significant association between SOFA score and AKI. The meta-analysis of 3 studies gave mean differences of 1.66 in favor of the AKI group (95% CI 1.12 - 2.21). The heterogeneity was low (Tau2 result = 0.06, I2 result = 22% with p = 0.28) and the significant results for the overall effect showed a value of p < 0.00001. 

Conclusion: The SOFA score has the potential to be a good predictor of AKI development in COVID-19 patients, with a significant mean difference.

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Author Biographies

  • Nicolas Daniel Widjanarko, Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

    Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

  • Erich Tamio, Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

    Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

  • Steven Alvianto, Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

    Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

  • Nadhea Debrinita Surya, Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

    Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

  • Rexel Kuatama, Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

    Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

  • Maria Riastuti Iryaningrum, Department of Internal Medicine, Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

    Department of Internal Medicine, Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

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Published

2023-06-09

How to Cite

1.
Sequential organ failure assessment (SOFA) score as a predictor of acute kidney injury in COVID-19 patients: a systematic review and meta-analysis. Udayana In. Med. [Internet]. 2023 Jun. 9 [cited 2024 Jun. 17];7(1):19-26. Available from: https://jpdunud.org/index.php/JPD/article/view/206

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