Faktor resiko contrast induced nephropathy pada pasien yang menjalani prosedur coronary intervention

Authors

  • Yenny Kandarini Departemen/KSM Penyakit Dalam, Fakultas Kedokteran Universitas Udayana/RSUP Sanglah, Denpasar, Bali Indonesia
  • Putu Juni Wulandari Program Studi Pendidikan Dokter Spesialis Penyakit Dalam, Fakultas Kedokteran Universitas Udayana/RSUP Sanglah, Denpasar, Bali, Indonesia
  • Gede Wira Mahadita Departemen/KSM Penyakit Dalam, Fakultas Kedokteran Universitas Udayana/RSUP Sanglah, Denpasar, Bali Indonesia

DOI:

https://doi.org/10.36216/jpd.v5i1.148

Keywords:

risk, CIN, AKI, coronary intervention

Abstract

Background: Contrast-induced nephropathy (CIN) is a manifestation of acute kidney injury (AKI) that occurs after exposure to intravascular contrast media. This often occurs after cardiac catheterization or percutaneous coronary intervention (PCI). So it is important to know what risk factors can affect the occurrence of CIN in patients undergoing coronary intervention.

Objective: To determine the relationship of CIN risk factors to the incidence of CIN in patients undergoing coronary intervention.

Methods: Prospective cohort study of 50 patients undergoing coronary intervention at Sanglah Hospital in January - June 2019. Analysis bivariate using the chi square, if the condition is not fulfilled, analyze using Fisher test. Then, multivariate analysis with logistic regression was performed. Data analysis using SPSS software version 24.0.

Result: Of the 50 patients who underwent coronary intervention as many as 7 people experienced CIN. Risk factors that were statistically significant related to the incidence of CIN, including serum creatinin levels before treatment (RR, 1,53; 95% CI, 1,11-2,12; p = 0,001), and amount of contrast (RR, 6,074; 95% CI, 1,64-22,54; p = 0,015). Multivariate analysis with probability of CIN in patients with contrast ≥ 100 ml and serum creatinine> 1.5 (p = 66%).

Conclusion: there was a statistically significant relationship between serum creatinin levels and the amount of contrast with the incidence of CIN in patients undergoing coronary intervention.

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Author Biographies

  • Yenny Kandarini, Departemen/KSM Penyakit Dalam, Fakultas Kedokteran Universitas Udayana/RSUP Sanglah, Denpasar, Bali Indonesia

    Departemen/KSM Penyakit Dalam, Fakultas Kedokteran Universitas Udayana/RSUP Sanglah, Denpasar, Bali Indonesia

  • Putu Juni Wulandari, Program Studi Pendidikan Dokter Spesialis Penyakit Dalam, Fakultas Kedokteran Universitas Udayana/RSUP Sanglah, Denpasar, Bali, Indonesia

    Program Studi Pendidikan Dokter Spesialis Penyakit Dalam, Fakultas Kedokteran Universitas Udayana/RSUP Sanglah, Denpasar, Bali, Indonesia

  • Gede Wira Mahadita, Departemen/KSM Penyakit Dalam, Fakultas Kedokteran Universitas Udayana/RSUP Sanglah, Denpasar, Bali Indonesia

    Departemen/KSM Penyakit Dalam, Fakultas Kedokteran Universitas Udayana/RSUP Sanglah, Denpasar, Bali Indonesia

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Published

2021-06-30

How to Cite

1.
Faktor resiko contrast induced nephropathy pada pasien yang menjalani prosedur coronary intervention. Udayana In. Med. [Internet]. 2021 Jun. 30 [cited 2024 Nov. 8];5(1):20-5. Available from: https://jpdunud.org/index.php/JPD/article/view/148

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